Manipal Hospitals

Sepsis in newborns

1 Min Read

Sepsis in newborns

Sepsis in newborns, known as neonatal sepsis, is a serious condition caused by a systemic infection in infants, typically occurring within the fi...

Treatments Available at

Sepsis in newborns: Symptom, Causes, Diagnosis and Treatment

Sepsis in newborns, known as neonatal sepsis, is a serious condition caused by a systemic infection in infants, typically occurring within the first 28 days of life. It may result from bacterial, viral, or fungal infections acquired before, during, or after birth. Early recognition and prompt treatment are crucial to prevent complications. Manipal Hospitals provides specialised neonatal care and multidisciplinary management for neonatal sepsis

Symptoms of Sepsis in newborns

Sepsis in newborns' symptoms may include poor feeding, lethargy, temperature instability, breathing difficulty, irritability, and reduced activity. Some newborns may develop jaundice, vomiting, abdominal distension, or seizures, indicating severe infection and possible progression.

How We Diagnose Sepsis in newborns

Diagnosis involves careful clinical assessment along with laboratory investigations. Blood cultures are essential to identify the causative organism. Additional tests include complete blood count, C-reactive protein, procalcitonin, and blood gas analysis. In selected cases, doctors may recommend cerebrospinal fluid examination, urine culture, and imaging studies to assess the extent of infection and detect complications.

Treatment Options

Management involves early administration of intravenous antibiotics after obtaining appropriate cultures. Supportive care includes fluid management, respiratory support, and continuous monitoring. Treatment is adjusted based on culture results and clinical response to ensure effective infection control.

What to Expect

At Manipal Hospitals, newborns suspected of sepsis are admitted to the neonatal intensive care unit (NICU) for close monitoring and prompt management. Initial evaluation includes assessment of vital signs, feeding patterns, and overall clinical status. Early stabilisation focuses on maintaining airway, breathing, and circulation, along with temperature regulation. Continuous monitoring of vital parameters and laboratory markers helps assess disease progression and response to treatment.

Doctors initiate empirical antibiotic therapy immediately after collecting cultures. Once laboratory results are available, treatment is tailored based on the identified organism and its sensitivity pattern.

Supportive care plays a crucial role and may include oxygen therapy, intravenous fluids, and nutritional support. In severe cases, advanced interventions such as mechanical ventilation or inotropic support may be required.

Treatment duration depends on the severity of infection and response to therapy. With early diagnosis and appropriate management, many newborns recover well. Regular monitoring and follow-up help detect long-term complications and support optimal growth and development.

or

Didn’t find what you were looking for?

Use our new search to get all your questions answered!

A Manipal Hospitals clinician available to help

Not sure what you’re looking for?

Get in touch with Manipal team!